About the PERC rule
PERC (Pulmonary Embolism Rule-out Criteria) is a clinical decision rule used in emergency and urgent-care settings to identify patients who are unlikely to have a pulmonary embolism (PE) and can reasonably avoid further testing such as D-dimer or CT pulmonary angiography. It is intended only for patients a clinician has already judged to have a low pretest probability of PE - typically under about 15% by clinical gestalt or a validated score such as the Wells criteria.
The eight criteria
- Age 50 years or older
- Heart rate 100 beats per minute or higher
- Oxygen saturation below 95% on room air
- Unilateral leg swelling
- Hemoptysis (coughing up blood)
- Surgery or trauma requiring general anesthesia in the past 4 weeks
- Prior pulmonary embolism or deep vein thrombosis
- Current hormone use, including oral contraceptives, hormone replacement therapy, or other exogenous estrogen
How the rule is applied
If none of the 8 criteria are present, the patient is PERC-negative: the rule considers PE unlikely enough that no further PE-specific testing is needed on this basis. If even one criterion is present, the patient is PERC-positive, and PE is not excluded - the clinician continues with the standard diagnostic pathway, typically D-dimer testing followed by imaging if the D-dimer is elevated. The rule is a binary gate, not a probability score: it does not distinguish between one positive criterion and several.
When to consult a professional
This tool performs the standard PERC arithmetic for education and reference. It is not a diagnosis and does not replace clinical assessment. Pulmonary embolism can be serious and even life-threatening, so any concerning symptoms - chest pain, shortness of breath, leg swelling, or coughing up blood - need evaluation by a qualified healthcare professional, and the decision to pursue or forgo further testing rests with the treating clinician.