About the Dihybrid Cross Calculator - Punnett Square
Genetics calculations apply Mendel's laws and population genetics theory to predict inheritance patterns, allele frequencies, and evolutionary dynamics.
Mendel's Laws recap
- Law of Segregation: each organism carries two alleles for each gene, and these segregate equally into gametes.
- Law of Independent Assortment: genes on different chromosomes (or far apart on the same one) assort independently during gamete formation. Linked genes violate this.
- Dominance: in simple Mendelian inheritance, one allele masks the other. Real traits often show incomplete dominance, codominance, or epistasis.
Hardy-Weinberg equilibrium
In an idealized population (no mutation, migration, selection, genetic drift; random mating), allele frequencies remain constant: p² + 2pq + q² = 1, where p and q are allele frequencies. Deviations from H-W expectations indicate evolutionary forces at work.
Punnett square interpretation
Each cell in the square represents one equally probable gamete combination. Probability of each genotype = count of cells with that genotype / total cells. For a monohybrid cross (Aa × Aa): 1/4 AA, 2/4 Aa, 1/4 aa → 3:1 dominant:recessive phenotype ratio in simple dominance.